Abstract
Evidence obtained in recent decades suggests that lipotoxicity and inflammation, through still undefined molecular mechanisms, are the main factors that link adipose tissue dysfunction to the development of non-alcoholic fatty liver disease (NAFLD), which comprises steatosis (NAFL), steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). Although mTORC1 and mTORC2, from both…