CV Lattes
ORCID
Abstract
The inflammasome is a multi-protein complex essential in innate immunity, activated by pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). The consequence of this activation is the cleavage of immature cytokines into their mature forms, IL-1² and IL-18, and eventually a type of inflammatory cell death known as pyroptosis. Although the NLRP3 inf…