Abstract
Voltage-sensitive sodium channels (NaV) are distributed in several excitable tissues of the human organism, being responsible in most cases for the genesis of the action potential in these cells, totaling a total of 9 subtypes. The Nav1.5 isoform is the isoform of the cardiac sodium channel, present abundantly in the myocardium, where its alpha subunit is encoded by the SCN5A gene. In ca…