Abstract
Alzheimer's disease (AD) is a gradual and progressive neurodegenerative disease characterized by extensive neuronal loss and deposits of neurofibrillary tangles and senile plaques. ADAM10 is the main ±-secretase capable of acting on the non-amyloidogenic pathway of amyloid precursor protein (APP) cleavage and, therefore, preventing the formation of ²-amyloid peptide (A²), one of the patho…