Abstract
Chagas disease is caused by the protozoan Trypanosoma cruzi, which resides in the digestive tract of insects such as triatomines and is transmitted by the intestinal contents of this vector. The metabolism of the amino acid Proline in T. cruzi is one of the essential pathways for its survival, being a precursor of Krebs cycle intermediates through the oxidation of proline to 1-pyrroline-…