CV Lattes
ORCID
Abstract
NRF2 is a transcription factor that plays a central role in the cellular response to oxidative stress. Mutations in the KEAP1/NRF2 pathway are relatively common in lung cancer and are often associated with poor patient prognosis. This is due to resistance to major treatments, such as chemotherapy and immunotherapy, since antioxidant genes are induced, protecting tumor cells against cell d…