Abstract
The STimulator of INterferon Genes (STING) pathway represents a fundamental component of the innate immune system (Hopfner and Hornung 2020), orchestrating the detection of cytosolic DNA and the initiation of immune responses. Typical STING activation initiates a signaling cascade triggering tank-binding kinase 1 (TBK1)/interferonregulatory factor 3 (IRF3) and nuclear factor kappa B (NF-k…