Abstract
MAIT cells are T lymphocytes V±7.2+CD161hiMR1+CD4-CD3+ that present semi-invariant chains in the TCR receptors and were initially described in mucosal regions. From this description, they were termed Mucosal-Associated Invariant T cells (MAIT cells). In these regions, under homeostatic conditions, they respond to metabolites from the riboflavin biosynthesis pathway (5-OP-RU) produced by c…