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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina (FMB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Carolina Rodrigues Tonon in research grants and scholarships supported by FAPESP.
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Doxorubicin is a chemotherapy drug used to treat several types of cancer, with high effectiveness; however, its toxicity in several organs may limit clinical use. Peripheral muscles toxicity is multifactorial and not well stablished, but doxorubicin appears to alter muscle energy metabolism, leading to increased anaerobic metabolism and muscle atrophy. Muscle mass loss is a prognostic mar…
Doxorubicin is a chemotherapy drug used to treat several types of cancer, with high effectiveness, but can cause toxicity in several organs, limiting its use. Toxicity to peripheral muscles is multifactorial and not well stablished, but doxorubicin appears to alter muscle energy metabolism, leading to an increase in anaerobic metabolism. Loss of muscle mass is a prognostic marker in these…
Doxorubicin is a widely used chemotherapy drug, but its use may be limited due to side effects, such as cardiotoxicity, which can lead to heart failure, a chronic and irreversible disease, with high morbidity and mortality rates. The activation of matrix metalloproteinases, which are enzymes responsible for the degradation of the extracellular matrix, appear to be involved in the pathophy…
| 1 / 1 | Ongoing grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 3 / 3 | All research grants and scholarships |
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