Graduation at Biotechnology from the Federal University of Paraíba (2019). Master's degree in Sciences, with emphasis on Immunology and Pathophysiology from the Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo (USP). Currently a doctoral candidate in Sciences at the Graduate Program in Clinical Oncology, Stem Cells and Cell Therapy at the Faculty of Medicine of Ribeirão Preto-USP, working on the development of cell therapy against solid tumors. (Source: Lattes Curriculum)
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Therapy based on the adoptive transfer of T cells expressing chimeric antigen receptors (CAR) have been showing good results in safety and efficacy against B cell malignancies. However, efficacy is still limited in solid tumors, mainly due to mechanisms of immunosuppression, hypoxia , nutrient deprivation and low infiltration of immune cells in the tumor microenvironment. Therefore, a com…
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