CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Undergraduate student in Biotenology at the University of São Paulo (2020 - 2025). I am currently a FAPESP scholarship holder with a project entitled Study of the mechanism of action and resistance to pyrazinamide in Mycobacterium tuberculosis at the Applied Structural Biology Laboratory of the Microbiology Department (ICB - USP) led by Prof. Dr. Marcio Bertacine Dias. (Source: Lattes Curriculum)
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Tuberculosis is a high-impact disease, diagnosed in 10.6 million patients and with a fatality rate of 1.3 million people in 2022 alone. The main drugs used to combat the disease are: isoniazid, rifampicin, ethambutol and pyrazinamide. Various studies have been carried out to understand the mechanism of action of these drugs, but there is no consensus on pyrazinamide (PZA). Two hypotheses …
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