Abstract
Paracoccidioidomycosis (PCM) is a granulomatous mycosis caused by fungi of the genus Paracoccidioides, belonging to the Ajellomycetaceae family. These fungi are thermodimorphic, meaning they undergo a transition from mycelium to yeast within the host. During infection, the fungus is exposed to various stress conditions, including drastic pH changes in the phagolysosome and hypoxic environ…