Abstract
Pediatric cancer, although rare, is the leading cause of death from diseases in children and adolescents. Bone tumors account for 4% to 8% of cases, with osteosarcoma being the most common bone tumor in childhood. Although osteosarcoma has a five-year survival rate of approximately 60-70% in patients with localized disease, this rate is much lower in cases of metastasis. In addition, the …