Carlos Daniel Marques Santos Simões in research grants and scholarships supported by FAPESP.
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The student's internship at the Federal University of Ceará is expected to begin in July 2025. Until then, the scholarship student will be involved in a project aimed at identifying the cross-reactivity of T-cell receptors (TCRs) through the structural analysis of antigenic peptides. Cross-reactivity occurs when a TCR is capable of recognizing multiple different peptides, leading to diver…
Recent advances in understanding T-cell-mediated immune responses have enabled the development of innovative tumor therapies and vaccines that leverage these cells' responses against viral antigens. The interaction between T-cell receptors (TCRs) and epitopes presented as peptides bound to an MHC molecule (pMHC) is the key event underpinning T-cell-based immunotherapies. However, despite …
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