Abstract
The present project aims to synthesize N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide, an intermediate in the synthesis of the drug Ranolazine®, used in the treatment of chronic angina. The synthesis of this intermediate will be carried out through the reaction of piperazine and 2-chloro-N-(2,6-dimethylphenyl)acetamide, with the main goal of transitioning the reaction from conventiona…