Abstract
Ovarian cancer (OC) is one of the most common and lethal gynecological tumors in the global female population. The high-grade serous type is the most frequent and the major contributor to the high mortality rates of the disease. The etiology of OC is multifactorial, but about 10 to 15% of cases are related to mutations in DNA repair genes, especially BRCA1 and BRCA2. The treatment of OC i…