Abstract
Proton pump inhibitors (PPIs) are among the most prescribed medications worldwide. PPIs induce microbiota modulation like what is observed in animal models of obesity and human obesity. However, PPIs can modulate microbiota without the need for a high-fat diet or weight gain. In previous studies, we investigated the effect of a 60-day PPI treatment on Toll-like Receptor 4 (TLR-4) signalin…