Abstract
Domestic dogs are the main urban reservoirs of Leishmania infantum, the causative agent of Visceral Leishmaniasis (VL) in the Americas. In endemic regions for VL, the number of cases in humans is associated with the canine infection rate. In Canine Leishmaniasis (LCan), sick dogs mount an inefficient cellular immune response (Th1) to combat the parasite concomitant with an increase in hum…