CV Lattes
ORCID
Abstract
Amyotrophic Lateral Sclerosis (ALS) is a lethal neurodegenerative disease that affects 0.01% of the global population. The disease causes intrinsic changes that lead to the death of motor neurons and muscle atrophy, resulting in muscle weakness and paralysis in more advanced stages. Clinical data show that ~50% of patients with ALS present non-motor symptoms, raising the hypothesis that d…