CV Lattes
ORCID
Abstract
Cardiotoxicity is a common adverse effect of oncological treatments, which can permanently compromise cardiac function and reduce patient survival. Protease-activated receptor type 1 (PAR1), encoded by the F2r gene, is a G-protein-coupled receptor with essential roles in processes such as hemostasis, inflammation, and vascular responses. It is activated by proteases such as thrombin, cath…