Abstract
The KIR2DL4 receptor, primarily expressed in Natural Killer (NK) cells, can transmit activating and inhibitory signals to the NK cell, depending on the ligand interacting with it. The KIR2DL4 gene exhibits copy number polymorphism as well as allelic diversity. This diversity, whether in sequence or the number of gene copies present in an individual, may influence the function of KIR2DL4 r…