Abstract
Metyrapone, an inhibitor of adrenal corticosteroid synthesis, has been shown to reduce both conditioned and unconditioned defensive responses in male rats. In conditioned fear, corticosterone appears to modulate dopamine release in the basolateral amygdala (BLA) through activation of mineralocorticoid receptors (MR) in the ventral tegmental area (VTA). However, the relationship between co…