Abstract
Antiphospholipid syndrome (APS) is an autoimmune disease defined by arterial, venous, or microcirculation thrombotic manifestations and obstetric complications, which occur in the presence of positivity for one or more antiphospholipid antibodies (aPL): lupus anticoagulant (LA), anticardiolipin antibody (aCL) and/or anti-¿2-glycoprotein-1 antibody (a¿2GP1). These antibodies create a proth…