Abstract
Genome integrity is continuously challenged by DNA lesions in all organisms. Thus, a functional DNA repair mechanism is essential for cell viability. DNA repair processes include the nucleotide exchange repair (NER), base exchange repair (BER), mismatch repair (MMR), single-strand annealing (SSA), homologous recombination (HR) and non-homologous end-joining (NHEJ). The heterodimeric endon…