Abstract
Alpha-synuclein (a-syn) is a protein of 140 amino acid residues that plays multiple roles in the synaptic activity of vertebrates. Adverse conditions or mutations can lead to the polymerization of this protein into amyloid fibrils, which are associated with certain neurodegenerative diseases known as synucleinopathies. For example, a-syn is one of the main components of amyloid plaques in…