Abstract
Introduction: Alzheimer's Disease (AD), the leading cause of dementia, exhibits a growingprevalence due to population aging. Sporadic AD is multifactorial, with both genetic (such asthe ApoE ¿4 allele) and environmental contributions. Diagnosis using biomarkers, particularlythose based on beta-amyloid (BA) peptide and tau protein, has been evolving towards lessinvasive methods, such as bl…