Abstract
Glioblastoma (GBM) is the most frequent, malignant, and lethal subtype among primary central nervous system tumors, accounting for 60% of the cases. They present high infiltration capacity and a poor prognosis, with an average survival of 12-15 months, reaching up to 5 years for 7.2% of the cases, declining to 2% in elderly patients. According to CBTRUS, the incidence of cases is 3.23 per…