Abstract
Triiodothyronine (T3), the active form of thyroid hormone (TH), plays a crucial role in regulating metabolism and maintaining energy homeostasis. Its metabolic action occurs primarily through interaction with nuclear receptors (TR¿1, TR¿2, TR¿1, and TR¿2), by which T3 regulates gene expression and function in various tissues such as adipose tissue (AT), heart, and blood vessels. Hypothyro…