Abstract
Sickle cell retinopathy (SCR) is the most significant ophthalmological complication in relation to ocular morbidity in sickle cell disease. This complication occurs due to vaso-occlusion of the ocular microvasculature, resulting from endothelial activation, inflammatory cascades, and adhesion and coagulation. Consequently, neovascularization can occur, eventually leading to vitreous hemor…