CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from the Adventist University of São Paulo (2009). In 2011 and 2015, completed his master's and doctorate degrees, respectively, in the discipline of Rheumatology at the Department of Medicine at Federal University of Sao Paulo - UNIFESP (Brazil), where he studied autoantibodies against IMPDH, which generates the "rods rings" pattern in the HEp-2-IFA test. From 2015 to 2017, he developed a Post-Doctorate at the Functional Genomics Sub-Unit of the Department of Physiology, Anatomy and Genetics (DPAG) at the University of Oxford (UK), where he described the cellular and physiological function of RR structures, also called cytoophidium (cellular snakes). He currently works as Affiliated Professor in the Discipline of Rheumatology at UNIFESP-EPM where he develops a project that aims to deplete pathogenic autoantibodies with gene editing. Since 2023, he has also served as Professor in the Department of Biomedical Sciences at the Catholic University of North (UCN) in Chile. (Source: Lattes Curriculum)
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The insertion of nucleic acids such as DNA plasmids or RNA fragments, aiming for genomic editing, into peripheral blood mononuclear cells (PBMC), which include plasma cells, is a difficult task, mainly due to low efficiency. Several methods are commercially available, so the objective of this work will be to test the different methods of inserting nucleic acids into plasma cells, to find …
Myasthenia Gravis (MG) is an autoimmune disease resulting from the action of autoantibodies against nicotinic acetylcholine receptors (nAChRs), interfering with the proper communication between the neurotransmitter acetylcholine (ACh) released by the axon and its nAChR receptor, expressed by the muscle fiber. The detection of anti-nAChR autoantibodies has 100% specificity for the diagnosi…
(Only some records are available in English at this moment)
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