Abstract
Trypanosoma cruzi, the etiologic agent of Chagas disease, is an intracellular parasite known for over a century. In order to infect host cells and complete their reproductive cycle, it needs to perform recognition, adhesion and invasion of these cells. The trans-sialidase family is the largest gene family of the parasite, comprising about 1,400 genes and pseudogenes, the gp85/trans-sialid…