CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Medical degree from Universidade Estadual de Campinas (1991) and PhD at Clinical Medicine from Universidade Estadual de Campinas (2000). Has experience in Medicine, focusing on Medicine, acting on the following subjects: dry eye, lacrimal gland, hormone diseases, gene therapy and Sjögren's syndrome. Between 1995 and 1997 concluded a research fellowship at Schepens Eye Research Institute / Harvard Medical School. In 2011 concluded a postdoctoral fellowship at NIH where he studied the application of gene therapy for diseases of the lacrimal gland and ocular surface . He is full professor and member of the post-graduate program of Ophthalmology , Otorhinolaryngology ,Head & Neck Surgery of FMRP- USP , Editor in-Chief of ABO, Former Head of the Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, FMRP -USP (2016-2019) . He is currently a member of ARVO , TFOS , BRAVO and CBO . In literature metric has more than 110 publications, a range of 2094 and 3899 citations and H index between 25 and 32 depending on the queried database. http://orcid.org/0000-0001-9888-7313 , http://www.researcherid.com/rid/D-6002-2011 (Source: Lattes Curriculum)
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Primary Sjögren's Syndrome (PSS) affects the ocular surface, oral health and has systemic manifestations, including neuropathies, independent of other diseases. The pathophysiological causes and mechanisms are poorly understood. Due to the frequency of SSp in the population and the difficulties in diagnosing and treating refractory cases, information on environmental influences, pathophys…
Corneal diseases are among the leading causes of blindness and the mechanisms of injury and repair are largely concentrated in the epithelium and lacrimal secretion. However, the target mediators for possible therapeutic interventions in modulating repair are unknown. In the corneal epithelium, healing is promoted by insulin and growth factors and mediated by a good trophic and neural str…
Tears and saliva play multiple roles in health. These secretions moisten, lubricate, nourish and protect the ocualr surface aond mouth, respectively. The tears helps in vision and saliva in speech and swallowing food . Moreover, both control microbial populations and promote the renovation and repair of tissues. Therefore, the lacrimal and salivary dysfunction, or a combination of both …
The aim of this proposal is to establish a platform for the development of topical delivery systems that ensure the targeted and sustained release of drugs to the epithelial tissue that forms the skin and the cornea. The design of drug delivery systems for topical treatment should take into account the integrity of the epithelium where they will be applied, the layer of this epithelium in…
(Only some records are available in English at this moment)
According to the literature, the prevalence of dry eye disease varies considerably depending on the studied population and associated factors. But still there are no epidemiological studies on the prevalence of this disease in the Brazilian and Latin American population. Currently, we use the results of international studies to lead to dry eye disease in our country. So an epidemiological…
Ocular diseases have high prevalence and significant impact on life quality. From Dry Eye Syndrome (DES) to the Retinal Degenerations, almost all eye diseases had a substantial epidemiology and pathophysiology knowledge increase on recent decades, in addition to the acquisition of a vast therapeutic arsenal, however commonly with a palliative and repeated use. In this sense, molecular med…
Tears and saliva play multiple roles in health. These secretions moisten, lubricate, nourish and protect the ocular surface and mouth, respectively. The tears helps in vision and saliva in speech and swallowing food . Moreover, both control microbial populations and promote the renovation and repair of tissues. Therefore, the lacrimal and salivary dysfunction, or a combination of both may…
(Only some records are available in English at this moment)
Dry eye and dry mouth are consequences of exocrine glands dysfunction. Those conditions may respond with modulation of peroxidase superfamily enzymes expression and action, however the specific role of different peroxidases was never explored. The aim of this study is to identify and distinguish the members of peroxidase superfamily in LG in rats and to evaluate the capacity to interfere …
| 1 / 1 | Ongoing research grants |
| 14 / 9 | Completed research grants |
| 13 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 29 / 18 | All research grants and scholarships |
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