CV Lattes
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Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Science and Biology at the Faculdade de Ciências e Letras Padre Anchieta (2002), master's degree in Molecular Biology from the Universidade Federal de São Paulo (2007) and a PhD in the Molecular Biology from the Universidade Federal de São Paulo (2012) is currently a postdoctoral fellow at the Universidade Federal do ABC. He has experience in biochemistry with emphasis on Bioenergetics, acting on the following topics: mitochondrial bioenergetics, tellurium compounds, thiol groups of proteins, gene expression, fluorescence microscopy, flow cytometry and cell death. (Source: Lattes Curriculum)
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Cell proteins undergoes turnover by means of digestion and the resulting amino acids are used for synthesis of new proteins. However, the digestion of proteins in cells generates peptides which, in specific cases, have signaling function and may lead to changes in the profile of gene expression and gene silencing. The cell degestion of proteins can occur in the proteassomes that degradate…
Literatura data about organotelluranes reveals that these compounds have efficient antioxidant properties, as well as the ability to react with thiol group of proteins. In a previous work (Pessoto et al., Dissertação de Mestrado e Chem. Res. Toxicol., 2007, 20, 1453-1461), our research group analized the effect of organotelluranes, RT-03 e RT-04, in rat liver mitochondria. The effects on…
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