CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate in Biomedical Sciences at Universidade Luterana do Brasil (2007) and PhD in Biotechnology at the Butantan Institute (2013). Posdoc in a recombinant BCG project for Pertussis (2013-2016). Posdoc in the production of recombinant protein NS1 from Zika virus as a diagnostic tool. Co-supervisor and lecturer in the Biotechnology program (USP-IB). Currently work as Researcher at the Laboratório de Desenvolvimento de Vacinas supervising projects in vaccine development, recombinant protein expression, immunology and biotechnology involving CRISPR/Cas. Experience in molecular biology, biotechnology, bioprocess, microbiology, immunology, recombinant protein production, in vitro assays, in vivo assays focusing in vaccine development. (Source: Lattes Curriculum)
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Bacillus of Calmette and Guérin (BCG) is a live attenuated vaccine of the pathogenic strain Mycobacterium bovis. Its emergence occurred from subsequent cultures of the strain in a medium containing bovine bile, which resulted, empirically, in the attenuation of virulence and pathogenicity in animal models. In the following years, BCG became widely used, being the only vaccine against tube…
BCG is one of the most widely used vaccines in the world. BCG has many attractive characteristics that make it an interesting vector in the presentation of heterologous antigens and, consequently, in the development of new vaccines. In addition, several studies have shown that immunization with BCG induces nonspecific protection against other infectious diseases. This protection indicates…
The BCG vaccine, the only one available to prevent tuberculosis, was developed at the beginning of the 20th century by Albert Calmette and Camille Guérin. BCG is a live-attenuated vaccine generated through successive cultures of the pathogenic Mycobacterium bovis. It prevents tuberculosis in a safe and effective way in children, however, the protection guaranteed by the vaccine in teenage…
Schistosomiasis is a parasitic disease of severe morbidity caused by parasites of the genus Schistosoma. The disease affects millions of people around the world, especially in developing countries, including Brazil. To date, there is no preventive vaccine to combat the disease and, thus, the control of the disease has been based solely on praziquantel, a drug that although effective, does…
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