CV Lattes
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Centro Universitário Saúde ABC (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduation in Biological Sciences Medical Modality from the Federal University of São Paulo (Unifesp), Master´s Degree and Doctorate (Ph.D.) obtained from the Postgraduation Program in Molecular Biology of the Federal University of São Paulo (Unifesp). Post-doctoral research was carried out at the Department of Cellular and Molecular Medicine at the University of California San Diego (UCSD), with funding from an American PEW Scholarship. Full Professor of the Discipline of Biochemistry at Centro Universitário Faculdade de Medicina do ABC (FMABC) and Associate Professor of the Discipline of Molecular Biology Unifesp. Permanent Advisor of the Postgraduation Programs in Molecular Biology Unifesp and Health Sciences FMABC. Coordinator of the Biomedicine Undergraduate Course at the Centro Universitário Faculdade de Medicina do ABC (FMABC). Experience in Biochemistry with emphasis on Molecular Biology. Research Projects: Molecular Biology of Cancer and Evaluation of Extracellular Matrix Alterations, working mainly on the following topics: Heparanase, Proteoglycans, Heparan Sulfate, and Heparin Biosynthesis, Phage Display Technology and Peptides with Therapeutic Potential. (Source: Lattes Curriculum)
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Understanding the molecular mechanisms involved in the development of tumors and tumor metastases is essential to generate knowledge that will allow the early detection and alternatives more effective for cancer treatment. Heparan sulfate proteoglycan (PGHS) plays an essential role in the tumor development processes. The enzyme heparanase (HPSE) comprises an endo-²-glucuronidase that degr…
The intervertebral disc degenerative process is an aberrant response to progressive structural deficiency. This process occurs as a result of biochemical alterations and can, eventually, develop with age, smoke habit, excessive weight, diabetes or genetic and epigenetic factors. The main alteration in the disease is the progressive loss of proteoglycans, water and collagen of nucleus pulp…
(Only some records are available in English at this moment)
The incidence rates of breast cancer are high in Brazil, despite advances in diagnosis and treatment. Moreover, the high recurrence of breast cancer is directly associated with the spread of tumor cells, which can lead to distant metastases. Some risk factors for breast cancer development are well established, like genetic factors with mutation in genes such as BRCA1 and BRCA2, TP53 and P…
| 8 / 4 | Completed research grants |
| 4 / 1 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 13 / 5 | All research grants and scholarships |
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