CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Farmácia from Faculdades Adamantinenses Integradas (2005), master's at Pharmacology from Universidade de São Paulo (2009) and doctorate at Farmacologia from Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (2012). Has experience in Pharmacy, focusing on Pharmacy, acting on the following subjects: diabetes mellitus, interação fármaco-receptor, agonismo e antagonismo farmacológicos, alzheimer and alfa 1d-adrenoceptores. (Source: Lattes Curriculum)
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Cardiovascular diseases result from atherosclerotic lesions and account for 31% of the world mortality. A major risk factor for atherosclerosis is smoking, which enhances the atherogenic process upon the activation of aryl hydrocarbon receptors (AhR) evoked by cigarette smoke contaminants. These receptors belong to the bHLH/PAS protein superfamily and induce the expression of pro-atheroge…
By activating AT1 receptors, angiotensin II (Ang II) induces the endothelial release of tumor necrosis factor-± (TNF-±), which evokes pro-atherogenic effects mediated by NAD(P)H oxidase-derived superoxide anion (O2-). Despite the pro-atherogenic effects mediated by AT1 receptors, the ACE2 - Angiotensin-(1-7) [Ang-(1-7)] - Mas axis evokes vaso-and atheroprotective effects. In fact, the chr…
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