Abstract
Multiple Sclerosis (MS) is among the neurological diseases with higher mundial incidence (30 cases/100,000 inhabitants). MS cause demyelination areas and axonal damage in the Central Nervous System (CNS) due to autoimmune response developed by Th1, Th17 and Tc lymphocytes. Experimental autoimmune encephalomyelitis (EAE) it is the main model to study. The involvement of mast cells in MS/EA…