Abstract
The question of title will be answered by Mycobacterium spp infection of non macrophages cell artificially enucleated (cytoplasts). Enucleation interrupts the gene transcription and partially mRNA processing, arresting the signaling dependent of cell nucleus. Slow growth pathogenic mycobacteria, as M. tuberculosis and M. Avium, survive within cells in fagossomos little acidified and non-…