Fernando Pradella in research grants and scholarships supported by FAPESP.
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Multiple Sclerosis (MS) is an autoimmune disease of the Central Nervous System (CNS) characterized by inflammation and neurodegeneration. Inflammation can be initiated by transmigration of autoreactive T lymphocytes and other leukocytes through the Blood-Brain Barrier (BBB), resulting in demyelination, degeneration and axonal damage to the white and gray matter of the CNS; 1) MS usually a…
Guillain-Barré Syndrome is a human peripheralnervous system acute inflammatory disease. The disease may culminatein paresis of the whole patient body or even in its death.Despite the evolution of the treatment in the last decade, acute inflammatory autoimmune diseases of peripheral nervous system (PNS) are still a concern due to the considerable morbidity and mortality. The current treatm…
The Experimental autoimmune neuritis (EAN) is considered the experimental model of Guillain-Barré's syndrome. The EAN is an autoimmune disease characterized by the infiltration of mononuclear cells into the endoneural space. There is an activation of auto-reactive cells against peripheral myelin compounds. This response in characterized mainly by lymphocytes Th1 and/or Th17, which culmina…
The experimental autoimmune neuritis (EAN) serves as a model for studying the Guillain-Barré syndrome. It is an autoimmune and demyelinating disease caused by T CD4 lymphocytes Th1/Th17. The present study is design to understand the effect of G-CSF on the evolution of EAN. The G-GSF is a hematopoietic factor with a important immunoregulatory effect of plasmacytoid dendritic cell and in th…
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) that is currently attributed to self-sustaining autoimmune mechanisms. Most of the knowledge regarding the autoaggressive mechanisms of MS has been obtained through experiments performed in its murine model, the Experimental Autoimmune Encephalomyelitis (EAE). EAE is considered a CD4+ T-cell med…
| 1 / 1 | Ongoing scholarships in Brazil |
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
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