CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto de Psiquiatria Doutor Antonio Carlos Pacheco e Silva (IPq) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Medicina from Faculdade de Medicina de Ribeirão Preto - USP (1984), master's at Neurologia from Escola Paulista de Medicina - UNIFESP (1990) and ph.d. at Neurology from Universidade Federal de São Paulo (1992). Has experience in Medicine, focusing on Neurology, acting on the following subjects: epilepsia do lobo temporal, temporal lobe epilepsy, epilepsy surgery, esclerose hipocampal and hippocampal sclerosis. (Source: Lattes Curriculum)
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Health systems form a complex structure whose understanding and modeling involve multiple factors and their relationships. Brazil's demographic diversity makes Health Management an even more challenging scenario. On the other hand, overcoming them can produce significant advances for Health in Brazil and worldwide. Advanced Artificial Intelligence (AI) methods have generated significant d…
Nearly half of the patients with epilepsy have poor seizure control, even after more than a century of advances in pharmacological treatment. For some of these drug-resistant cases, surgery may be the indicated treatment. In these cases, surgical success is directly linked to the correct location of the epileptogenic zone (EZ; i.e., the brain area responsible for seizure generation), and …
Nearly half of the patients with Epilepsy have poor seizure control, even after more than a century of advances in pharmacological treatment. For some of these drug-resistant cases, surgery may be the indicated treatment. In these cases, surgical success is directly linked to the correct location of the epileptogenic zone (EZ; i.e., the brain area responsible for seizure generation), and …
Respiratory disorders and cerebrovascular diseases are highly prevalent worldwide, and there are mounting clinical and epidemiological evidence of a strong causal relation between them. A better comprehension of such interaction could result in advances in treatment and prevention of both conditions, with considerable public health impact.Stroke is the second leading cause of death and th…
(Only some records are available in English at this moment)
Non-invasive brain stimulation therapies, such as transcranial magnetic stimulation (TMS) and transcranial electrical current stimulation (tES), are promising alternatives for treating depression. In recent years, a variant of TMS, intermittent theta-burst stimulation (iTBS) over the prefrontal cortex, has gained prominence. In this scenario, individualized neuromodulation strategies, aim…
Epilepsy is a neurological condition with high prevalence that significantly impacts the quality of life of millions of people around the world. This research project centres on temporal lobe epilepsy (TLE), which is one type of focal epilepsy frequently resistant to pharmacological therapies and commonly associated with hippocampal sclerosis (HE). The main aim of this study is to execute…
Cognitive impairments and psychiatric disorders are highly prevalent in patients with temporal lobe epilepsy (TLE), which is characterized precisely by several changes in electroencephalographic activity. In fact, brain oscillatory activity has been correlated with several cognitive functions. Specifically, oscillations in the gamma frequency (30-70 Hz) are observed during the performance…
The neural network hypothesis proposes that depression or resilience are determined by the integrated function of multiple brain regions, but most of the evidence for this proposal is still indirect. Recently, patterns of oscillatory activity of large-scale brain networks involved in the processing of stressor controllability, discrimination between stress or safety and motivational valen…
Depression is the most prevalent psychiatric comorbidity in Temporal Lobe Epilepsy (TLE). Clinical and experimental works point to dysfunctional activity in neural circuits shared by both pathologies. In this sense, discriminating these circuits involved in ELT associated with depression is still a challenge, but investigated circuits associated with depressive-like behaviors per se could…
(Only some records are available in English at this moment)
Understanding local brain circuits and how they adapt and maintain their own dynamics in the face of stimuli is essential to unravel basic and pathological mechanisms. Epilepsy is a disability condition associated with severe cognitive deficits, characterized by changes in neural networks, with excessive and hypersynchronous activity. Furthermore, seizures propagate through brain networks…
Magnetic resonance imaging (MRI) is an important non-invasive tool for the evaluation of several conditions. In drug-resistant epilepsies, surgical outcome depends largely on complete removal of the epileptogenic region, making MRI crucial for surgical planning. Cortical dysplasias, one of the most common pathological findings in young drug-resistant patients, can remain undetected by MRI…
How do memories persist? Network activity during sleep is thought to support memory through a process known as systems consolidation. In this process, neuronal circuits are reorganized, and new cell assemblies are bound with neurons that were previously activated during acquisition of the memory itself. In particular, reorganization between the hippocampus and the medial prefrontal cortex…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 27 / 13 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 51 / 21 | Completed scholarships in Brazil |
| 7 / 6 | Completed scholarships abroad |
| 90 / 45 | All research grants and scholarships |
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