CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from São Paulo State University (UNESP). Master's degree in General and Applied Biology with emphasis on Cellular and Structural Plasticity (UNESP). Ph.D. in Biological Sciences (Genetics) from the Institute of Biosciences of Botucatu (UNESP) with a sandwich Ph.D. period at the Research Center for Molecular Biology and Genetics - Biogem (Ariano Irpino, Italy) and Harvard Medical School (Boston, USA) under the supervision of Da-Zhi Wang, seeking to understand the post-transcriptional mechanisms associated with cancer cachexia. Completed a Post-Doctorate in the Department of Immunology (ICB-USP), applying computational analyses to understand inflammation and immunoregulation processes. Currently, she is developing her second Post-Doctoral project at the School of Pharmaceutical Sciences (FCF-USP), analyzing the genome and germline variants in patients with familial hypercholesterolemia. Has experience in molecular genetics and bioinformatics analyses (exome, transcriptome, microRNAome), mainly focusing on metabolic diseases and cancer. (Source: Lattes Curriculum)
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Brown adipose tissue (BAT) is known for its thermogenic function due to the expression of mitochondrial uncoupling protein 1 (Ucp1). Under certain conditions, white adipose tissue (WAT) can express Ucp1, acquiring thermogenic characteristics through a phenomenon known as browning. The activation of BAT and browning process have been considered effective strategies in combating obesity and…
Familial hypercholesterolemia (FH) is a genetic disease characterized by high concentrations of low-density protein cholesterol (LDL-c), increasing cardiovascular risk. The molecular diagnosis of HF is based on analyzing genes that cause autosomal dominant HF. However, although several functional mutations associated with HF have already been described in the LDLR, APOB, and PCSK9, other …
The current pandemic of the Coronavirus respiratory disease 2019 (COVID-19) represents a state of international public emergency. The virus causing the disease is called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been circulating throughout the world, triggering clinical manifestations ranging from asymptomatic cases to severe acute respiratory syndrome and death…
Skeletal muscle differentiation, or myogenesis, is a highly orchestrated process in which mononucleated muscle precursor cells, the myoblasts, undergo proliferation. Upon differentiation, they withdraw from the cell cycle, migrate, align with each other, and subsequently fuse to form terminally differentiated multinucleated myotubes. Myogenesis deregulation is related to important skeleta…
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