Francine Attié de Castro

CV Lattes

Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Post doc at SANOFI-R&D Innovation. PhD in Toxicology by University of São Paulo (Brazil). Was visiting researcher at Leiden University (Pharmacology team). Experience: Pharmacokinetics and metabolism studies (in vivo, in silico), pre-clinical and clinical pharmacokinetics studies. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Scholarships in Brazil

Completed (most recent)

Enantioselectivity on the kinetic disposition and metabolism of cyclophosphamide and dose ajustment of busulfan in patients undergoing stem cell transplantation, BP.DR

Scholarships abroad

Completed (most recent)

Abstract
Busulfan (BU) is an alkylating agent commonly administered in a pre-conditioning hematopoietic stem cell transplantation (HSCT). BU is a drug with narrow therapeutic index and high interindividual variability in pharmacokinetics. Therapeutic monitoring of oral BU is necessary for success of bone marrow transplantation and it is already well described in literature. Conventional therapeut…
Development of a population pharmacokinetic model using the NONMEN software (non-linear mixed effect model) for oral busulfan dosage individualization in patients undergoing hematopoietic stem cell transplantation, BE.EP.DR

Virtual Library in numbers * Updated data on August 09, 2025

Total / Available in English

1 / 1	Completed scholarships in Brazil
1 / 1	Completed scholarships abroad
2 / 2	All Scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Vera Lúcia Lanchote

Keywords used by the researcher

Biological Sciences Pharmacology

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Abstract