Mariane Serra Fraguas

CV Lattes ResearcherID Google Scholar Citations

Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da USP (HCMRP). Hemocentro de Ribeirão Preto (Institutional affiliation from the last research proposal)
Birthplace: Brazil

graduate at Ciências Biológicas - modalidade Bacharelado from Faculdade de Ciências Agrárias e Veterinárias / UNESP/ Jaboticabal (2008), graduate at Ciências Biológicas - modalidade: Licenciatura from Faculdade de Ciências Agrárias e Veterinárias / UNESP/ Jaboticabal (2006) and master's at Sciences et Technologies, Santé from Universite de Versailles Saint-Quentin-en-Yvelines (2009). Has experience in Medicine, focusing on Pathological Anatomy and Clinical Pathology, acting on the following subjects: células-tronco, ensino médio, cão, linfoma and citologia aspirativa por agulha fina (caaf). (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Scholarships in Brazil

Completed (most recent)

Abstract
Embrionary Stem Cells (ESC) are capable of self-renewal keeping the pluripotent state. These properties make ESC a potential tool for Regenerative Medicine. Recently, the generation of induced pluripotent stem cells (iPSs) by somatic cell genetic reprogramming (trough Oct4, Sox2, c-Myc and Klf4 genes), created new expectations for cellular therapy. However, beside the genetic risks associ…
Manipulation of inhibitory pathways of pluripotency induction aiming efficiency increase in iPSs generation process, BP.DD

Scholarships abroad

Completed (most recent)

Abstract
Adult somatic cells can be reprogrammed into induced pluripotent stem cells (IPSCs) by the ectopic expression of pluripotency-related transcription factors (TF), such as, Oct4, Nanog, Sox2 and c-Myc. MicroRNAs (miRs) are non-coding RNAs involved in the post-transcriptional regulation of a wide range of targets, and may thus, influence cell fate by modulating distinct signaling pathways an…
MiR-29a target two central components of active DNA demethylation, TET1 and TDG: potential mechanism during reprogramming, BE.EP.DD

Virtual Library in numbers * Updated data on August 16, 2025

Total / Available in English

1 / 1	Completed scholarships in Brazil
1 / 1	Completed scholarships abroad
2 / 2	All Scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Marco Antonio Zago

Keywords used by the researcher

Biological Sciences Genetics

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Abstract

Abstract