Miguel José Rangel Junior

• Abstract

  The resident-intruder paradigm has been broadly used in compartmental trials to minimize animal participation in aggressive contexts and in those he has to defend himself, allowing the study of the physiological mechanisms regulations these behaviors. The role of sex hormones in the rodent's central nervous system in the modulations of social behaviors is well described in the literature,…

  Analysis of active neurons expressing ESR1 receptors in agression and social defense in male mice, BP.IC

• Abstract

  In rodents, subcortical nuclei have been showed as important areas in reproductive and social behaviors. Our group has focused on mapping brain areas involved in aggressive and defensive behaviors in animals exposed to the resident-intruder paradigm. Circuits encompassing amygdalar, hypothalamic and brain stem sites have been outlined as involved in the mediation of aggressive and defens…

  Functional analysis of the neural circutis involved in aggression and social defeat in rodents, BP.PD

• Abstract

  Animals present risk assessment behaviors when exposed to the environments where they had been socially defeated, a response called contextual defense to social defeat. In the present work, we aim to explore the putative paths that mediate these responses. Similar to what has been shown for anti-predatory defense, the dorsal premammillary nucleus is critical for social defense and, at the…

  Role of anterior thalamus and its cortical targets in conditioned defensive behavior to the social defeat context, BP.DR

(Only some records are available in English at this moment)

• Abstract

  The dorsal premammillary nucleus (PMd) represents one of the most mobilized sites during social agonistic encounters and provides strong projections to the dorsal part of the periaqueductal gray (dPAG) and the ventral part of the anteromedial thalamic nucleus (AMv). In the present study, we plan to study the role of the PMd and its main targets (i.e., dPAG and AMv) in the innate and conte…

  Role of the dorsal premammillary nucleus and its main targets in the expression of innate defensive responses and the acquisition of contextual fear memory during social defeat, BE.EP.DR