Abstract
Cytosolic tryparedoxin peroxidase is an antioxidant protein involved in a pathway for hydroperoxide detoxification restricted to the trypanosomatids. This pathway is distinct from the counterpart present in the host offering options for the development of a more specific therapy for Chagas disease treatment. Another tryparedoxin peroxidase (TcMPx) was identified in the mitochondrion, toge…