Patricia Miralda Cazita

• Abstract

  CETP is a glycoprotein known to mediate the exchange the cholesteryl ester from high-density lipoprotein (HDL) to apoB-rich lipoproteins triglycerides. The CETP activity is inversely related to HDL-cholesterol (HDL-C). Recently, the increase in HDL-C levels by inhibition of CETP activity became a target of new drug developments. However, investigations utilizing CETP inhibitors have so fa…

  The role of CETP (cholesterol ester transfer protein) on the uptake, cellular distribution and hepatic excretion of lipopolysaccharide, AP.R

• Abstract

  Sepsis is a systemic inflammatory response to infection eliciting high mortality rate which is a serious health problem. Despite numerous studies seeking for therapeutic alternatives, the mechanisms involved in this disease remain elusive. In this study was evaluated the influence of cholesteryl ester transfer protein (CETP), a glycoprotein that promotes the transfer of lipids between lip…

  CETP Lowers TLR4 expression which Attenuates the inflammatory response induced by LPS and Polymicrobial sepsis, PUB.ART

• Abstract

  The cholesteryl ester transfer protein (CETP) is an important component of reverse cholesterol transport. In plasma, CETP is mostly bound to HDL particles, and is considered a key molecule in this lipoprotein metabolism. Due to the structural homology between CETP and lipopolysaccharide binding protein (LBP) which operates in the innate immune response, raised the hypothesis that CETP cou…

  Analysis of participation of cholesteryl ester transfer protein (CETP) in inflammatory response triggered by LPS and mediated by Toll-like receptor 4 (TLR4) in macrophages, AP.R

(Only some records are available in English at this moment)

• The role of Cholesteryl Ester Transfer Protein (CETP) in the inflammatory response triggered by LPS and mediated by Toll-Like receptor 4 (TLR4) in macrophages, BP.MS