Abstract
Lung cancer is strongly associated with smoking habits and it is ranked as the first cause of cancer-related deaths worldwide, being non-small cell (NSCLC) the most frequent histological type.The standard treatment for advanced NSCLC is the combination of a platinum compound with a third generation cytotoxic agent such as vinorelbine, gemcitabine, paclitaxel, docetaxel and pemetrexed. Thi…