CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biomedicina from Universidade Metodista de São Paulo (2011) and doctorate at Biologia Molecular from Universidade Federal de São Paulo (2016). Has experience in Physiology, focusing on Renal Physiology, acting on the following subjects: inibidores do sra, nefropatia diabética and receptor de (pro)renina. (Source: Lattes Curriculum)
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Obesity is defined as a disorder of the systems regulating body weight and is often associated with Metabolic Syndrome (MS), defined as a set of diseases that severely affect the organism. Both obesity and MS are responsible for the development of many diseases such as dyslipidemia, hypertension, inflammation, nephropathy and others. Among the mechanisms involved in the development of the…
INTRODUCTION: Renin and prorenin bind to (pro)renin receptor ((P)RR) resulting in increased synthesis of Ang II and activation of MAP kinases family ERK 1/2. The (P)RR was cloned in mesangial cells (MC) and experimental data strongly suggest that it has a central role in diabetic glomerulosclerosis by Ang II-dependent and independent pathways. We observed previously that silencing (P)RR …
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