Abstract
The biologically active gas, nitric oxide (NOÏ) is well recognized as an important modulator of vascular homeostasis with vasorelaxant, anti-aggregatory, and anti-proliferative properties. Interestingly, nitroxil (HNO), the one electron reduced and protonated form of NOÏ, is rapidly emerging as a new redox sibling of NOÏ, with distinct pharmacological actions and therapeutic advantages ov…