Abstract
The present project is an original research which will assess the histological response of bone tissue in contact with the Biosilicate containing a crystalline phase and a demineralized bovine bone named Bonefill ®. Will be used 84 rats (Rattus norvegicus, Wistar), weighing between 200 and 300 grams. Forty-two rats will undergo surgery for bilateral ovariectomy and forty-two for sham surg…